SCHEMBL14599951

SCHEMBL14599951

CS(C)(C)C(c1cc(-c2ccccc2)ccn1)S(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PLAU P00749 1/20 0.40
▸ NOTUM Q6P988 1/20 0.39
▸ FDPS P14324 1/20 0.39
▸ PIK3CA P42336 1/20 0.37
▸ F11 P03951 1/20 0.37
▸ EGFR P00533 1/20 0.36
▸ ASIC3 Q9UHC3 1/20 0.34
▸ LOXL2 Q9Y4K0 2/20 0.34
▸ PSEN1 P49768 2/20 0.34
▸ PSEN2 P49810 2/20 0.34
▸ APH1B Q8WW43 2/20 0.34
▸ NCSTN Q92542 2/20 0.34
▸ APH1A Q96BI3 2/20 0.34
▸ PSENEN Q9NZ42 2/20 0.34
▸ CTSA P10619 1/20 0.34
▸ LOXL3 P58215 1/20 0.33
▸ WNT3A P56704 1/20 0.33
▸ PORCN Q9H237 1/20 0.33
▸ COMT P21964 1/20 0.33
▸ ALK Q9UM73 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2737364 0.79 PLAU (0.43) PLAUNOTUMFDPSPIK3CAF11
SCHEMBL12915284 0.76 PLAU (0.41) PLAUNOTUMFDPSPIK3CAF11
SCHEMBL5168192 0.76 CHRNB2 (0.55) PLAUFDPSF11LOXL2
SCHEMBL14600595 0.76 CYP2E1 (0.40) ALK
SCHEMBL30559520 0.76 PLAU (0.43) PLAUNOTUMFDPSPIK3CAEGFR
SCHEMBL21645888 0.75 MAPT (0.42) PLAUNOTUMFDPSPIK3CAF11
SCHEMBL22166443 0.75 PLAU (0.40) PLAUNOTUMFDPSPIK3CAF11
SCHEMBL14600864 0.73 UHRF1 (0.46) PLAUFDPS
SCHEMBL14599966 0.73 NPC1 (0.41) LOXL2LOXL3
SCHEMBL5700203 0.73 PLAU (0.41) PLAUNOTUMFDPSPIK3CAEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070072001-A1 Luminescent device CANON KABUSHIKI KAISHA (JP) 2007-03-29 — — US disclosed
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