Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | BUB1 | O43683 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | PRKG2 | Q13237 | 2/20 | 0.40 |
| ▸ | CIT | O14578 | 1/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737364 | 0.80 | PLAU (0.43) | PLAUNOTUMFDPSPIK3CAEGFR | |
| SCHEMBL12915284 | 0.77 | PLAU (0.41) | PLAUNOTUMFDPSPIK3CAWNT3A | |
| SCHEMBL3714790 | 0.77 | PLAU (0.41) | PLAUNOTUMFDPSPIK3CAEGFR | |
| SCHEMBL28992891 | 0.77 | DYRK1A (0.60) | FDPSAAK1CYP3A4PRKG2CIT | |
| SCHEMBL14599951 | 0.76 | PLAU (0.40) | PLAUNOTUMFDPSPIK3CAWNT3A | |
| SCHEMBL21645888 | 0.76 | MAPT (0.42) | PLAUNOTUMFDPSPIK3CAEGFR | |
| SCHEMBL22166443 | 0.76 | PLAU (0.40) | PLAUNOTUMFDPSCYP3A4PIK3CA | |
| SCHEMBL12302767 | 0.76 | WNT3A (0.56) | WNT3A | |
| SCHEMBL30636785 | 0.74 | IRAK4 (0.46) | AAK1CITGAKMKNK1BMP2K | |
| SCHEMBL21153538 | 0.73 | AKT1 (0.43) | AAK1CYP3A4PRKG2CITGAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589425-A | Cathepsin L inhibitors | 百放英库医药科技(北京)有限公司 | 2023-08-15 | — | — | CN | disclosed |