SCHEMBL1460

SCHEMBL1460

O=c1nccc[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1414022 1.00 POLB (0.41)
Fluoride SCHEMBL28204776 0.97
SCHEMBL28094435 0.97
SCHEMBL28302405 0.97
Hydrochloric Acid SCHEMBL865815 0.97
Hydrogen Sulfide SCHEMBL28847244 0.97
Hydrochloric Acid SCHEMBL10435844 0.97
Bromide SCHEMBL30767150 0.97
SCHEMBL7569502 0.97
SCHEMBL338725 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16291 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12635405-B2 Quantum dot material and preparation method therefor, quantum dot display device, display apparatus, method for patterning quantum dot film, and method for fabricating quantum dot light-emitting device Beijing BOE Technology Development Co., Ltd; (CN) 2026-05-19 US claimed
CN-122070282-A Pyrazole-1-carboxamides as RIP1 kinase inhibitors 比西切姆有限公司 2026-05-19 CN claimed
EP-4741376-A1 NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Hansoh Biomedical Co., Ltd. (CN) 2026-05-13 EP claimed
CN-122011784-A Photo-curing type pyrimidine-terminated ketone-based silicone rubber material and preparation method thereof 山东大学 2026-05-12 CN claimed
CN-122017251-A Marker group for sarcopenia screening and diagnosis and application thereof 四川大学华西医院 2026-05-12 CN claimed
WO-2026090160-A2 CD4-TARGETED IL-15 MOLECULES AND METHODS OF USE GILEAD SCIENCES, INC. (US) 2026-04-30 WO claimed
US-12595282-B1 Method for synthesizing nucleotide strands HONGENE BIOTECH PTE. LTD. (SG) 2026-04-07 US claimed
EP-4704830-A2 MRGPRX2 INHIBITORS AND METHODS OF USE THEREOF Septerna, Inc. (US) 2026-03-11 EP claimed
US-12565493-B2 Method for preparing 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one BASF SE (DE) 2026-03-03 US claimed
US-12558357-B2 Tetrahydroquinazoline derivatives as selective cytotoxic agents MERCK SHARP & DOHME LLC (US) 2026-02-24 US claimed
EP-0166564-A2 Pyrimidone derivatives, preparation thereof and use thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-01-02 EP claimed
EP-0054866-B1 OXADIAZOLOPYRIMIDINE DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS CONTAINING SUCH AN OXADIAZOLOPYRIMIDINE DERIVATIVE F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1985-08-07 EP claimed
EP-0066440-B1 CHEMICAL PROCESS SMITHKLINE BECKMAN CORPORATION (US) 1985-07-31 EP claimed
EP-0137343-A2 Novel oxopyrimidine derivatives and pharmaceutical compositions containing them Taro Pharmaceutical Industries Ltd. (IL) 1985-04-17 EP claimed
EP-0054132-B1 PYRIMIDONES, THEIR PREPARATION AND MEDICINES CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1984-10-10 EP claimed
EP-0119560-A2 Hypohalite-based bleaching, cleaning and disinfecting agent with storing stability B. Braun-SSC AG (CH) 1984-09-26 EP claimed
US-4352933-A Chemical methods and intermediates for preparing substituted pyrimidinones SMITHKLINE BECKMAN CORPORATION (US) 1982-10-05 US claimed
EP-0058055-A2 Process for preparing substituted pyrimidinones and intermediates therefor SMITHKLINE BECKMAN CORPORATION (US) 1982-08-18 EP claimed
US-4289847-A 2-EQUIVALENT YELLOW COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-09-15 US claimed
US-4014879-A RING CLOSURE, NEUTRALIZATION; AMIDINE AND METHYLACETOACETATE IN A BASE CIBA-GEIGY CORPORATION (US) 1977-03-29 US claimed