⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1414022 | 0.97 | POLB (0.41) | — | |
| SCHEMBL1460 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL865815 | 0.95 | — | — | |
| Fluoride SCHEMBL28204776 | 0.95 | — | — | |
| SCHEMBL28094435 | 0.95 | — | — | |
| SCHEMBL338725 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL10435844 | 0.95 | — | — | |
| Hydrogen Sulfide SCHEMBL28847244 | 0.95 | — | — | |
| Bromide SCHEMBL30767150 | 0.95 | — | — | |
| SCHEMBL28302405 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222195-A1 | NOVEL THIAZOLO(4,5-D)PYRIMIDINE COMPOUNDS | AstraZeneca UK Limited (GB) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001025242-A1 | NOVEL THIAZOLO(4,5-D)PYRIMIDINE COMPOUNDS | ASTRAZENECA UK LIMITED (GB) | 2001-04-12 | — | — | WO | disclosed |
| US-4496728-A | Method for the production of 2-isopropyl-4-methyl-6-hydroxypyrimidine | CIBA-GEIGY CORPORATION (US) | 1985-01-29 | — | — | US | disclosed |
| US-4014879-A | RING CLOSURE, NEUTRALIZATION; AMIDINE AND METHYLACETOACETATE IN A BASE | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |