Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1460 | 0.97 | — | — | |
| SCHEMBL1414022 | 0.97 | POLB (0.41) | — | |
| Fluoride SCHEMBL28204776 | 0.95 | — | — | |
| SCHEMBL28302405 | 0.95 | — | — | |
| SCHEMBL28094435 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL865815 | 0.95 | — | — | |
| Hydrogen Sulfide SCHEMBL28847244 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL10435844 | 0.95 | — | — | |
| SCHEMBL7569502 | 0.95 | — | — | |
| SCHEMBL338725 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111902143-B | Inhibitors of calcium concentration increase in nerve cells | 东丽株式会社 | 2024-01-02 | — | — | CN | disclosed |