Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 13/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600176 | 0.90 | FKBP1A (0.41) | FKBP1ATMEM97ACE | |
| SCHEMBL14600150 | 0.90 | FKBP1A (0.39) | FKBP1ATMEM97ACECA12CA1 | |
| SCHEMBL8299273 | 0.86 | FKBP1A (0.41) | FKBP1AACE | |
| SCHEMBL14600154 | 0.85 | TMEM97 (0.38) | FKBP1ATMEM97ACE | |
| SCHEMBL14600152 | 0.84 | ACE (0.38) | FKBP1AACEMAPT | |
| SCHEMBL14600153 | 0.84 | ACE (0.38) | FKBP1AACEMAPT | |
| SCHEMBL5566810 | 0.79 | ACE (0.44) | TMEM97ACEMAPT | |
| SCHEMBL14600085 | 0.78 | TMEM97 (0.46) | TMEM97ACE | |
| SCHEMBL14600074 | 0.76 | PRSS1 (0.42) | TMEM97ACEMAPT | |
| SCHEMBL14600157 | 0.76 | ACE (0.41) | FKBP1AACEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169805-B2 | Captopril derivatives | NICOX S.A. (FR) | 2007-01-30 | — | — | US | disclosed |