SCHEMBL8299273

SCHEMBL8299273

C[C@H](CSC(=O)CN)C(=O)N1CCC[C@H]1C(=O)OCc1ccc(CON(O)O)cc1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 9/20 0.41
ACE P12821 5/20 0.37
REN P00797 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8303016 0.89 FKBP1A (0.41) FKBP1AACEREN
SCHEMBL14600155 0.86 FKBP1A (0.39) FKBP1AACE
SCHEMBL8303941 0.85 FKBP1A (0.39) FKBP1AACE
SCHEMBL8299272 0.85 FKBP1A (0.37) FKBP1AACEREN
SCHEMBL8299265 0.79 ACE (0.48) ACEREN
SCHEMBL14600176 0.76 FKBP1A (0.41) FKBP1AACE
SCHEMBL8301495 0.76 ACE (0.40) FKBP1AACEREN
SCHEMBL14600150 0.76 FKBP1A (0.39) FKBP1AACE
SCHEMBL11280672 0.76 FKBP1A (0.52) FKBP1AACE
SCHEMBL8300106 0.75 FKBP1A (0.38) FKBP1AACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004106300-A1 CAPTOPRIL DERIVATIVES NICOX S.A. (FR) 2004-12-09 WO disclosed