Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008418 | 0.92 | GFER (0.60) | GFERMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4664181 | 0.87 | MAPK14 (0.55) | MAPK14MAPK13MAPK12MAPK11PTK2 | |
| SCHEMBL14600246 | 0.87 | MAPK13 (0.53) | GFERMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL14600184 | 0.85 | ADORA1 (0.49) | GFERMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL14600443 | 0.85 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11PTK2 | |
| SCHEMBL14600238 | 0.85 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11PTK2 | |
| SCHEMBL14600240 | 0.84 | MAPK14 (0.62) | GFERMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5007787 | 0.83 | ADORA1 (0.52) | GFERMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5008343 | 0.83 | MEN1 (0.50) | GFERMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5012181 | 0.82 | ADORA1 (0.51) | GFERMAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |