Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.45 |
| ▸ | DHODH | Q02127 | 13/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666119 | 0.92 | ADORA1 (0.39) | ADORA1ADORA2AADORA2B | |
| SCHEMBL14600205 | 0.91 | ADORA1 (0.49) | ADORA1DHODHADORA2AADORA2BFABP3 | |
| SCHEMBL14600715 | 0.90 | DHODH (0.45) | ADORA1DHODH | |
| SCHEMBL14600203 | 0.88 | ADORA1 (0.42) | ADORA1DHODHADORA2AADORA2B | |
| SCHEMBL4666215 | 0.88 | ADORA1 (0.51) | ADORA1DHODH | |
| SCHEMBL14600448 | 0.87 | ADORA1 (0.43) | ADORA1DHODHADORA2AADORA2B | |
| SCHEMBL14600247 | 0.86 | ADORA1 (0.43) | ADORA1DHODHADORA2AADORA2B | |
| SCHEMBL14600244 | 0.85 | ADORA1 (0.44) | ADORA1DHODHFABP3FABP4 | |
| SCHEMBL4668528 | 0.83 | ADORA1 (0.53) | ADORA1DHODH | |
| SCHEMBL14600441 | 0.81 | ADORA1 (0.56) | ADORA1DHODHADORA2AADORA2BFABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |