Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 8/20 | 0.43 |
| ▸ | DHODH | Q02127 | 11/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600247 | 0.89 | ADORA1 (0.43) | ADORA1DHODHADORA2AADORA2B | |
| SCHEMBL14600435 | 0.87 | ADORA1 (0.45) | ADORA1DHODHADORA2AADORA2B | |
| SCHEMBL4667055 | 0.82 | ADORA1 (0.53) | ADORA1DHODHADORA2B | |
| SCHEMBL14600208 | 0.80 | ADORA1 (0.43) | ADORA1ADORA2AADORA2B | |
| SCHEMBL14600714 | 0.80 | DHODH (0.42) | ADORA1DHODHADORA2AADORA2B | |
| SCHEMBL4666119 | 0.79 | ADORA1 (0.39) | ADORA1ADORA2AADORA2B | |
| SCHEMBL14600449 | 0.79 | ADORA1 (0.46) | ADORA1DHODHADORA2AADORA2B | |
| SCHEMBL14600204 | 0.79 | ADORA1 (0.47) | ADORA1DHODHADORA2AADORA2B | |
| SCHEMBL14600205 | 0.78 | ADORA1 (0.49) | ADORA1DHODHADORA2AADORA2B | |
| SCHEMBL14600715 | 0.78 | DHODH (0.45) | ADORA1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |