Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600681 | 0.94 | DHODH (0.44) | DHODHGFERKEAP1NFE2L2MAPT | |
| SCHEMBL4666640 | 0.91 | DHODH (0.58) | DHODHKEAP1NFE2L2MAPTTP53 | |
| Hydrochloric Acid SCHEMBL4666221 | 0.91 | DHODH (0.57) | DHODHKEAP1NFE2L2MAPTTP53 | |
| SCHEMBL14600674 | 0.90 | DHODH (0.44) | DHODHGFERKEAP1NFE2L2MAPT | |
| SCHEMBL4668988 | 0.85 | DHODH (0.49) | DHODHKEAP1NFE2L2MAPTTP53 | |
| SCHEMBL4668570 | 0.84 | GFER (0.42) | DHODHGFERMAPTTP53FABP4 | |
| Hydrochloric Acid SCHEMBL4669539 | 0.83 | GFER (0.41) | DHODHGFERMAPTTP53FABP4 | |
| SCHEMBL14600683 | 0.83 | GFER (0.44) | DHODHGFERKEAP1NFE2L2MAPT | |
| SCHEMBL14600686 | 0.82 | FTO (0.40) | GFERMAPTTP53FABP4KMT2A | |
| SCHEMBL14600676 | 0.80 | DHODH (0.46) | DHODHKEAP1NFE2L2FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |