Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 8/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600687 | 0.90 | FABP3 (0.42) | FTOPDE4BMAPTFABP4FABP3 | |
| SCHEMBL14600690 | 0.90 | CLCN2 (0.40) | PDE4BMAPTTP53MEN1LMNA | |
| SCHEMBL14600694 | 0.89 | PDE4B (0.39) | FTOPDE4BMAPTTP53MEN1 | |
| SCHEMBL14600681 | 0.88 | DHODH (0.44) | FTOPDE4BGFERMAPTTP53 | |
| SCHEMBL14600499 | 0.87 | FABP3 (0.45) | PDE4BMAPTTP53FABP4FABP3 | |
| SCHEMBL14600486 | 0.86 | PDE4B (0.43) | FTOPDE4BGFERMAPTTP53 | |
| SCHEMBL14600271 | 0.83 | GRM5 (0.49) | FTOGFERMAPTMEN1LMNA | |
| SCHEMBL14600673 | 0.82 | DHODH (0.47) | GFERMAPTTP53MEN1LMNA | |
| SCHEMBL4668570 | 0.80 | GFER (0.42) | FTOPDE4BGFERMAPTTP53 | |
| Hydrochloric Acid SCHEMBL4669539 | 0.79 | GFER (0.41) | FTOPDE4BGFERMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |