Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667077 | 0.93 | NTRK1 (0.38) | NTRK1RXFP1CAPN1LMNA | |
| SCHEMBL14600469 | 0.91 | NTRK1 (0.44) | MPONTRK1DHODHHDAC6CAPN1 | |
| SCHEMBL14600998 | 0.91 | DHODH (0.46) | NTRK1DHODHHDAC6LMNAFABP4 | |
| SCHEMBL14601001 | 0.91 | NTRK1 (0.40) | MPONTRK1DHODHHDAC6CAPN1 | |
| SCHEMBL14600999 | 0.90 | FABP4 (0.44) | NTRK1DHODHHDAC6CAPN1TAS2R14 | |
| SCHEMBL14601000 | 0.89 | IGF2BP2 (0.39) | NTRK1DHODHHDAC6 | |
| SCHEMBL14600722 | 0.89 | SORT1 (0.41) | MPODHODHRXFP1LMNAAKR1C2 | |
| SCHEMBL14600214 | 0.83 | DHODH (0.44) | MPONTRK1DHODHHDAC6CAPN1 | |
| SCHEMBL14600468 | 0.82 | DHODH (0.40) | DHODHLMNA | |
| SCHEMBL4667857 | 0.81 | DHODH (0.42) | NTRK1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |