Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14642468 | 0.97 | TSHR (0.49) | TSHRKDM4EGLAL3MBTL1CNR1 | |
| SCHEMBL13510960 | 0.91 | TSHR (0.50) | TSHRKDM4EGLAL3MBTL1CNR1 | |
| SCHEMBL12081798 | 0.89 | TSHR (0.55) | TSHRKDM4EGLAL3MBTL1CNR1 | |
| SCHEMBL24244825 | 0.87 | TSHR (0.57) | TSHRKDM4EGLAL3MBTL1CNR1 | |
| SCHEMBL22199409 | 0.86 | MEN1 (0.41) | TSHRKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL23169072 | 0.86 | TSHR (0.49) | TSHRKDM4EGLAL3MBTL1CNR1 | |
| SCHEMBL21842294 | 0.86 | MEN1 (0.41) | TSHRKDM4ESMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL21311636 | 0.86 | TSHR (0.49) | TSHRKDM4EGLAL3MBTL1CNR1 | |
| SCHEMBL22388820 | 0.86 | ADRA1A (0.46) | TSHRKDM4EL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL14134341 | 0.86 | TSHR (0.49) | TSHRKDM4EGLAL3MBTL1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070020224-A1 | Protein-proteophore complexes | ASCENDIS PHARMA GMBH (DE) | 2007-01-25 | — | — | US | disclosed |
| US-20070020224-A1 | Protein-proteophore complexes | ASCENDIS PHARMA GMBH (DE) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070020224-A1 | Protein-proteophore complexes | PSMG3, PSME1, PSMD11 | TSHR 4498/4885KDM4E 3799/4885GLA 1344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.