Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.56 |
| ▸ | PLG | P00747 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13045424 | 0.94 | FOLH1 (0.56) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL16329971 | 0.94 | FOLH1 (0.56) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL13045386 | 0.93 | FOLH1 (0.49) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL16299304 | 0.93 | FOLH1 (0.55) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL14601079 | 0.92 | TDP1 (0.54) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL13045421 | 0.92 | TDP1 (0.54) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL13045436 | 0.90 | FOLH1 (0.48) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL13045432 | 0.89 | FOLH1 (0.48) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL13045443 | 0.89 | FOLH1 (0.48) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL16329973 | 0.89 | FOLH1 (0.56) | FOLH1PLGPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834144-B2 | Prion-specific peptoid reagents | NOVARTIS AG (CH) | 2010-11-16 | — | — | US | disclosed |