SCHEMBL14601142

SCHEMBL14601142

NC(N)(C(=O)O)c1ccc(O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.47
ESR2 Q92731 6/20 0.47
CYP3A4 P08684 5/20 0.47
ALDH1A1 P00352 3/20 0.47
BLM P54132 3/20 0.47
KIF11 P52732 3/20 0.43
TYR P14679 3/20 0.42
LMNA P02545 3/20 0.42
HPGD P15428 3/20 0.42
HSD17B10 Q99714 2/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA3 P07451 2/20 0.42
CA4 P22748 2/20 0.42
CA5A P35218 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CA5B Q9Y2D0 2/20 0.42
AR P10275 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL622048 0.80 CYP1A2 (0.54) CYP3A4ALDH1A1BLMKIF11HSD17B10
SCHEMBL20794387 0.79 BLM (0.46) ESR1ESR2CYP3A4ALDH1A1BLM
SCHEMBL5427934 0.77 BLM (0.53) ESR1ESR2CYP3A4ALDH1A1BLM
SCHEMBL23706076 0.77 BLM (0.53) ESR1ESR2CYP3A4ALDH1A1BLM
SCHEMBL24208279 0.77 BLM (0.53) ESR1ESR2CYP3A4ALDH1A1BLM
SCHEMBL11445392 0.76 BLM (0.43) ESR1ESR2CYP3A4ALDH1A1BLM
Hydrochloric Acid SCHEMBL5376244 0.76 BLM (0.52) ESR1ESR2CYP3A4ALDH1A1BLM
SCHEMBL4206889 0.75 CA2 (0.48) ESR1ESR2CYP3A4ALDH1A1BLM
Trifluoroacetic Acid SCHEMBL26092954 0.74 KIF11 (0.64) ESR1ESR2ALDH1A1KIF11LMNA
SCHEMBL9316418 0.74 BLM (0.50) ESR1ESR2CYP3A4ALDH1A1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007031698-A1 ASYMMETRIC SYNTHESIS OF PEPTIDES UNIVERSITY OF READING (GB) 2007-03-22 WO disclosed