Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13663681 | 0.86 | ACHE (0.61) | ACHENPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL10724144 | 0.85 | ACHE (0.77) | ACHENPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL18551055 | 0.83 | SMN1; SMN2 (0.57) | NPC1RAB9AHPGDALDH1A1TP53 | |
| SCHEMBL5047494 | 0.81 | ACHE (0.67) | ACHENPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL8054515 | 0.80 | HPGD (0.69) | ACHENPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL23440304 | 0.78 | ALDH1A1 (0.73) | ACHENPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL9500165 | 0.78 | ACHE (0.67) | ACHENPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL28855327 | 0.78 | ACHE (0.67) | ACHENPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL13504099 | 0.78 | SMN1; SMN2 (0.68) | ACHENPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL23440265 | 0.77 | ACHE (0.74) | ACHENPC1RAB9AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |