Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12043114 | 0.87 | KDM4E (0.64) | PKMKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL14602136 | 0.86 | MEN1 (0.65) | KMT2ALMNAALDH1A1KDM4EATM | |
| SCHEMBL1445522 | 0.84 | KDM4E (0.69) | PKMKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL16940596 | 0.76 | KDM4E (0.62) | KMT2ALMNAALDH1A1KDM4EATM | |
| SCHEMBL2525573 | 0.74 | KDM4E (0.84) | KMT2ALMNAALDH1A1KDM4EATM | |
| SCHEMBL14733477 | 0.74 | ALDH1A1 (0.47) | PKMKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL12043125 | 0.73 | ALDH1A1 (0.51) | PKMKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL16940595 | 0.69 | KDM4E (0.74) | KMT2ALMNAALDH1A1KDM4EATM | |
| SCHEMBL12043118 | 0.68 | ALDH1A1 (0.70) | PKMKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL12043094 | 0.65 | KDM4E (0.85) | KMT2ALMNAALDH1A1KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007035722-A2 | METHODS AND COMPOSITIONS FOR STIMULATING NEUROGENESIS AND INHIBITING NEURONAL DEGENERATION | NEURONASCENT, INC. (US) | 2007-03-29 | — | — | WO | disclosed |