Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CASP1 | P29466 | 1/20 | 0.65 |
| ▸ | CASP7 | P55210 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2525573 | 0.88 | KDM4E (0.84) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL14601359 | 0.86 | PKM (0.51) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL16940595 | 0.82 | KDM4E (0.74) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL12043094 | 0.79 | KDM4E (0.85) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL19495070 | 0.78 | MEN1 (0.63) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1445522 | 0.78 | KDM4E (0.69) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL12043096 | 0.78 | MEN1 (0.81) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL12043118 | 0.75 | ALDH1A1 (0.70) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL12043114 | 0.74 | KDM4E (0.64) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL14073368 | 0.74 | KDM4E (0.64) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007035722-A2 | METHODS AND COMPOSITIONS FOR STIMULATING NEUROGENESIS AND INHIBITING NEURONAL DEGENERATION | NEURONASCENT, INC. (US) | 2007-03-29 | — | — | WO | disclosed |