Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CFTR | P13569 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | VCP | P55072 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5585456 | 0.99 | MAPT (0.56) | RAB9AMAPTNPC1KDM4ECSNK2A1 | |
| SCHEMBL12297959 | 0.84 | CSNK2A1 (0.74) | RAB9AMAPTNPC1CSNK2A1MEN1 | |
| SCHEMBL12297485 | 0.83 | MAPT (0.55) | RAB9AMAPTNPC1CSNK2A1MEN1 | |
| SCHEMBL21708012 | 0.83 | GAA (0.66) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL12297489 | 0.82 | ALOX5 (0.60) | RAB9AMAPTNPC1KDM4ECSNK2A1 | |
| SCHEMBL12297488 | 0.82 | MEN1 (0.60) | RAB9AMAPTNPC1CSNK2A1MEN1 | |
| SCHEMBL4956917 | 0.82 | CSNK2A1 (0.64) | RAB9AMAPTNPC1CSNK2A1MEN1 | |
| SCHEMBL5464349 | 0.81 | MAPT (0.73) | RAB9AMAPTNPC1KDM4EMEN1 | |
| SCHEMBL10963704 | 0.81 | RAB9A (0.70) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL12297972 | 0.80 | ALOX5 (0.53) | RAB9AMAPTNPC1KDM4ECSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163952-B2 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-7163952-B2 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-16 | — | — | US | disclosed |