SCHEMBL14601447

SCHEMBL14601447

Sc1ccc(-c2ccc(-c3ccc(S)s3)s2)s1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
GLA P06280 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10471775 0.79 HSD17B1 (0.50) APPESR1ESR2KDM4ENPC1
SCHEMBL776508 0.75 DPP4 (0.53) APPKDM4EMAPT
SCHEMBL21023679 0.69 KDM4E (0.41) APPESR1ESR2KDM4ENPC1
SCHEMBL20860771 0.66 PIK3CA (0.41) KDM4ENPC1GLARAB9A
SCHEMBL22249956 0.65 APP (0.55) APPESR1ESR2KDM4ENPC1
SCHEMBL12878493 0.65
SCHEMBL8384237 0.65
SCHEMBL12973255 0.63 APP (0.55) APPESR1ESR2
SCHEMBL120939 0.60 NPC1 (0.50) APPESR2KDM4ENPC1GLA
SCHEMBL5889177 0.60 SNCA (0.48) APPESR1ESR2KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7186634-B2 Method for forming metal single-layer film, method for forming wiring, and method for producing field effect transistors SONY CORPORATION (JP) 2007-03-06 US disclosed