SCHEMBL21023679

SCHEMBL21023679

Sc1ccc(-c2ccc(S)s2)cn1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
PIK3CD O00329 2/20 0.35
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
MAP4K4 O95819 1/20 0.32
APP P05067 2/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
MKNK1 Q9BUB5 1/20 0.32
MKNK2 Q9HBH9 1/20 0.32
FLT3 P36888 1/20 0.30
LTA4H P09960 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20860771 0.80 PIK3CA (0.41) KDM4EALDH1A1GAAPIK3CDNPC1
SCHEMBL14601447 0.69 APP (0.33) KDM4ENPC1RAB9AAPPESR1
SCHEMBL16486899 0.67 NPC1 (0.50) ALDH1A1NPC1RAB9AMAP4K4
SCHEMBL10471775 0.67 HSD17B1 (0.50) KDM4EALDH1A1MEN1NPC1RAB9A
SCHEMBL1256082 0.65 CYP3A4 (0.57) KDM4EALDH1A1GAAPIK3CDMEN1
SCHEMBL10053498 0.64 ALDH1A1 (0.55) KDM4EALDH1A1GAAPIK3CDMEN1
SCHEMBL22249956 0.63 APP (0.55) KDM4EALDH1A1MEN1NPC1RAB9A
SCHEMBL12887194 0.63 SNCA (0.34)
SCHEMBL6986430 0.62 KDM4E (0.72) KDM4EALDH1A1GAANPC1RAB9A
SCHEMBL969071 0.62 NPC1 (0.47) KDM4EALDH1A1GAAPIK3CDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3168848-B1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, AND TERPYRIDINE COMPOUND OR ESTERIFICATION PRODUCT THEREOF FUJIFILM CORP (JP) 2019-05-22 EP disclosed