Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 5/20 | 0.37 |
| ▸ | MMP13 | P45452 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP12 | P39900 | 2/20 | 0.33 |
| ▸ | MMP14 | P50281 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12900879 | 0.91 | NPC1 (0.39) | NPC1RAB9APOLBCYP2C9HTT | |
| SCHEMBL9891919 | 0.88 | NPC1 (0.41) | NPC1RAB9APOLBCYP2C9HTT | |
| SCHEMBL13605588 | 0.87 | HTT (0.38) | NPC1RAB9APOLBCYP2C9HTT | |
| SCHEMBL12831322 | 0.86 | HTT (0.39) | NPC1RAB9APOLBCYP2C9HTT | |
| SCHEMBL11995525 | 0.86 | MMP2 (0.36) | HTTSMN1; SMN2MMP2MMP13LMNA | |
| SCHEMBL13064094 | 0.84 | NPC1 (0.49) | NPC1RAB9APOLBCYP2C9HTT | |
| SCHEMBL17914112 | 0.84 | PGR (0.46) | HTTSMN1; SMN2MMP2MMP13NR3C1 | |
| SCHEMBL12646212 | 0.81 | NPC1 (0.53) | NPC1RAB9APOLBCYP2C9HTT | |
| SCHEMBL13822221 | 0.81 | NPC1 (0.42) | NPC1RAB9APOLBCYP2C9SMN1; SMN2 | |
| SCHEMBL13605583 | 0.80 | HTT (0.43) | NPC1RAB9APOLBCYP2C9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072000-A1 | Organic electroluminescent element and manufacturing method thereof | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2007-03-29 | — | — | US | disclosed |