Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.39 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5585421 | 0.99 | KMT2A (0.40) | KMT2AMEN1HTTALKBH1NPSR1 | |
| SCHEMBL5585686 | 0.82 | KMT2A (0.47) | KMT2AMEN1HTTALKBH1NPSR1 | |
| SCHEMBL5585411 | 0.81 | FFAR1 (0.44) | KMT2AMEN1HTTNPSR1CPT2 | |
| SCHEMBL5585795 | 0.79 | MAPT (0.46) | KMT2AMEN1HTTMAPTNPC1 | |
| SCHEMBL5585432 | 0.79 | MRGPRX4 (0.51) | KMT2AMEN1HTTCPT2CPT1A | |
| SCHEMBL5585655 | 0.79 | GCGR (0.49) | ADAMTS4MMP13ALOX5ALDH1A1NR4A2 | |
| SCHEMBL5585812 | 0.77 | MEN1 (0.40) | KMT2AMEN1HTTNPSR1CPT2 | |
| SCHEMBL5585255 | 0.77 | TRPM8 (0.47) | KMT2AMEN1HTTNPSR1CPT2 | |
| SCHEMBL14601453 | 0.75 | ALDH1A1 (0.42) | KMT2AMEN1HTTCPT2CPT1A | |
| SCHEMBL5585488 | 0.75 | KMT2A (0.44) | KMT2AMEN1NPSR1FFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163952-B2 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-7163952-B2 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-16 | — | — | US | disclosed |