Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601860 | 0.87 | CA12 (0.42) | GRK6CA12CA1CA2CA9 | |
| SCHEMBL8941496 | 0.84 | HSD17B10 (0.47) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL31411936 | 0.84 | CA1 (0.54) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL12125057 | 0.83 | ALDH1A1 (0.48) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL2068454 | 0.78 | ALDH1A1 (0.54) | GRK6ALDH1A1MAPTL3MBTL1NPSR1 | |
| SCHEMBL28193965 | 0.76 | SMN1; SMN2 (0.46) | CA12CA1CA2ALDH1A1HTT | |
| SCHEMBL2042318 | 0.75 | ALDH1A1 (0.47) | GRK6ALDH1A1MAPTL3MBTL1NPSR1 | |
| Potassium Ion SCHEMBL28222970 | 0.74 | ALDH1A1 (0.50) | GRK6ALDH1A1MAPTL3MBTL1NPSR1 | |
| Methyl Alcohol SCHEMBL28171303 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MAPTL3MBTL1NPSR1GLA | |
| SCHEMBL2524621 | 0.73 | L3MBTL1 (0.58) | GRK6ALDH1A1MAPTL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7161022-B2 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-7161022-B2 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |