Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.52 |
| ▸ | TNNI3K | Q59H18 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4947374 | 0.83 | TNNI3K (0.46) | KAT6ATNNI3KSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9058916 | 0.82 | TP53 (0.53) | KAT6ASMN1; SMN2ALDH1A1LMNAPKM | |
| SCHEMBL24271983 | 0.81 | KAT6A (0.54) | KAT6ASMN1; SMN2ALDH1A1LMNAPKM | |
| SCHEMBL4948322 | 0.81 | TNNI3K (0.45) | KAT6ATNNI3KSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL14773591 | 0.81 | TP53 (0.52) | KAT6ASMN1; SMN2ALDH1A1LMNAPKM | |
| SCHEMBL29909928 | 0.81 | KEAP1 (0.62) | KAT6ATNNI3KALDH1A1LMNAL3MBTL1 | |
| SCHEMBL12561642 | 0.81 | KEAP1 (0.62) | KAT6ATNNI3KALDH1A1LMNAL3MBTL1 | |
| SCHEMBL13592998 | 0.81 | TP53 (0.52) | KAT6ASMN1; SMN2ALDH1A1LMNAPKM | |
| SCHEMBL12517460 | 0.81 | TNNI3K (0.79) | TNNI3KEGFR | |
| SCHEMBL5610159 | 0.79 | CA1 (0.62) | KAT6ALMNAPKMPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7161022-B2 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-7161022-B2 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |