Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DBH | P09172 | 1/20 | 0.53 |
| ▸ | KRAS | P01116 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986048 | 0.81 | MAOB (0.56) | DBHKRASLMNAHTTMAPT | |
| SCHEMBL3492139 | 0.81 | MAOB (0.56) | DBHKRASLMNAHTTMAPT | |
| SCHEMBL5512237 | 0.80 | RAB9A (0.53) | RAB9ALMNAHTTMAPTALDH1A1 | |
| SCHEMBL5512233 | 0.80 | RAB9A (0.53) | RAB9ALMNAHTTMAPTALDH1A1 | |
| SCHEMBL14601569 | 0.80 | RAB9A (0.44) | DBHKRASRAB9ALMNAHTT | |
| SCHEMBL1447168 | 0.79 | DBH (0.55) | DBHKRASABCG2LMNAHTT | |
| SCHEMBL1446863 | 0.79 | MAPT (0.57) | DBHKRASRAB9AABCG2LMNA | |
| SCHEMBL1446864 | 0.79 | MAPT (0.57) | DBHKRASRAB9AABCG2LMNA | |
| SCHEMBL14601582 | 0.78 | ABCG2 (0.45) | KRASABCG2LMNAMAPTGAA | |
| SCHEMBL7372393 | 0.78 | KMT2A (0.46) | DBHLMNAHTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7161022-B2 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-7161022-B2 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |