Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DBH | P09172 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601586 | 0.80 | DBH (0.53) | RAB9APOLBALDH1A1MAPTMEN1 | |
| SCHEMBL30283174 | 0.79 | TPMT (0.55) | POLBMAPTGAASMN1; SMN2HTT | |
| SCHEMBL12190691 | 0.73 | NPC1 (0.49) | RAB9APOLBALDH1A1MAPTMEN1 | |
| SCHEMBL30360234 | 0.71 | POLB (0.48) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11120481 | 0.71 | ALDH1A1 (0.47) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11120482 | 0.71 | ALDH1A1 (0.47) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28977415 | 0.71 | POLB (0.48) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30283180 | 0.70 | MAPT (0.50) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL28992151 | 0.70 | MAPT (0.46) | RAB9APOLBALDH1A1MAPTMEN1 | |
| SCHEMBL12190686 | 0.70 | NPC1 (0.47) | RAB9APOLBALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7161022-B2 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-7161022-B2 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |