Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.34 |
| ▸ | RAC1 | P63000 | 1/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9861917 | 0.90 | KDM4E (0.42) | SMN1; SMN2ALDH1A1TSHRPOLBGLA | |
| SCHEMBL11067019 | 0.88 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1TSHRPOLBGLA | |
| SCHEMBL15850774 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TSHRPOLBGLA | |
| SCHEMBL6119760 | 0.86 | ADRB2 (0.44) | SMN1; SMN2ALDH1A1TSHRPOLBGLA | |
| SCHEMBL17897742 | 0.84 | SELL (0.41) | SMN1; SMN2ALDH1A1TSHRPOLBGLA | |
| SCHEMBL10093727 | 0.84 | ADRB2 (0.45) | SMN1; SMN2ALDH1A1TSHRPOLBGLA | |
| SCHEMBL6023992 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1TSHRPOLBGLA | |
| SCHEMBL21615516 | 0.78 | POLB (0.43) | ALDH1A1TSHRPOLBGLAGAA | |
| SCHEMBL15761590 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TSHRPOLBGLA | |
| SCHEMBL24801799 | 0.78 | KDM4E (0.42) | SMN1; SMN2ALDH1A1FFAR4KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183488-A1 | METHOD OF MANIPULATING HYDROPHILICITY AND HYDROPHOBICITY OF CONVENTIONAL DYE MOLECULES FOR TRACER APPLICATIONS | SAUDI ARABIAN OIL COMPANY (SA) | 2023-06-15 | — | — | US | disclosed |
| US-7163944-B2 | Cyclic diamine compound and pharmaceutical containing the same | KOWA CO., LTD. (JP) | 2007-01-16 | — | — | US | disclosed |