Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14641302 | 1.00 | CASP3 (0.53) | CASP3HRH3SCN9ARENCASP1 | |
| SCHEMBL5645873 | 0.94 | CASP3 (0.56) | CASP3HRH3PREPMMEACE | |
| SCHEMBL5649938 | 0.82 | SCN9A (0.42) | HRH3SCN9AAADAT | |
| SCHEMBL5649936 | 0.82 | SCN9A (0.42) | HRH3SCN9AAADAT | |
| SCHEMBL14641301 | 0.80 | CASP3 (0.64) | CASP3CASP1MMEACE | |
| SCHEMBL5650545 | 0.80 | CASP3 (0.64) | CASP3CASP1MMEACE | |
| SCHEMBL14603133 | 0.80 | CASP3 (0.64) | CASP3CASP1MMEACE | |
| SCHEMBL6599837 | 0.79 | CASP3 (0.66) | CASP3MMEACE | |
| SCHEMBL5645465 | 0.79 | SCN9A (0.43) | HRH3SCN9A | |
| SCHEMBL14603132 | 0.77 | CASP3 (0.61) | CASP3CASP1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166586-B2 | Sulfonamide lactam inhibitors of FXa and method | BRISTOL MYERS SQUIBB CO. (US) | 2007-01-23 | — | — | US | disclosed |