Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | ACE | P12821 | 8/20 | 0.59 |
| ▸ | MME | P08473 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5650545 | 1.00 | CASP3 (0.64) | CASP3ACEMMECASP1ALDH1A1 | |
| SCHEMBL14603133 | 1.00 | CASP3 (0.64) | CASP3ACEMMECASP1ALDH1A1 | |
| SCHEMBL6601810 | 0.97 | CASP3 (0.68) | CASP3ACEMMECASP1 | |
| SCHEMBL6394661 | 0.93 | CASP3 (0.58) | CASP3ACEMMECASP1ALDH1A1 | |
| SCHEMBL14603132 | 0.90 | CASP3 (0.61) | CASP3ACEMMECASP1ALDH1A1 | |
| SCHEMBL14641489 | 0.90 | CASP3 (0.61) | CASP3ACEMMECASP1ALDH1A1 | |
| SCHEMBL14603128 | 0.90 | CASP3 (0.61) | CASP3ACEMMECASP1ALDH1A1 | |
| SCHEMBL6199732 | 0.89 | CASP3 (0.60) | CASP3CASP1ALDH1A1GAACTSL | |
| SCHEMBL6599837 | 0.88 | CASP3 (0.66) | CASP3ACEMME | |
| SCHEMBL28777681 | 0.86 | CASP3 (0.54) | CASP3ACEMMECASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166586-B2 | Sulfonamide lactam inhibitors of FXa and method | BRISTOL MYERS SQUIBB CO. (US) | 2007-01-23 | — | — | US | disclosed |