Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAP2 | P11137 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14604052 | 0.89 | MAP2 (0.40) | MAPK8LMNAMAP2ALDH1A1USP2 | |
| Hydrochloric Acid SCHEMBL14604154 | 0.88 | MAP2 (0.40) | MAPK8LMNAMAP2ALDH1A1USP2 | |
| SCHEMBL14604008 | 0.85 | MAPK8 (0.48) | MAPK8 | |
| SCHEMBL3634689 | 0.85 | MAPK8 (0.42) | MAPK8LMNAALDH1A1USP2TSHR | |
| SCHEMBL12984854 | 0.84 | LMNA (0.44) | MAPK8LMNAMAP2ALDH1A1TSHR | |
| SCHEMBL14604240 | 0.84 | MAPK8 (0.37) | MAPK8LMNAMAP2ALDH1A1USP2 | |
| SCHEMBL14603875 | 0.84 | MAPK8 (0.49) | MAPK8ALDH1A1TSHRHSD17B10KDM4E | |
| SCHEMBL3631272 | 0.84 | MAPK8 (0.44) | MAPK8LMNAALDH1A1USP2TSHR | |
| SCHEMBL14604333 | 0.83 | MAPK8 (0.51) | MAPK8LMNAALDH1A1KMT2AHPGD | |
| SCHEMBL14603856 | 0.83 | MAPK8 (0.49) | MAPK8ALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2731932-A1 | AMINOMETHYL QUINOLONE COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2014-05-21 | — | — | EP | disclosed |
| WO-2013007676-A1 | AMINOMETHYL QUINOLONE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-01-17 | — | — | WO | disclosed |