SCHEMBL1460673

SCHEMBL1460673

NP(=O)(O)OCc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.70
CETP P11597 3/20 0.53
SRC P12931 1/20 0.49
PDPK1 O15530 1/20 0.49
MTOR P42345 1/20 0.49
ALPG P10696 1/20 0.49
PTK2B Q14289 1/20 0.49
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
IDO1 P14902 1/20 0.46
FOLH1 Q04609 1/20 0.46
LAP3 P28838 3/20 0.46
ANPEP P15144 1/20 0.46
AGXT P21549 1/20 0.45
PARP10 Q53GL7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL15169626 0.98 TSHR (0.68) TSHRCETPSRCPDPK1MTOR
SCHEMBL6685550 0.83 TSHR (0.76) TSHRCETPSRCPDPK1MTOR
SCHEMBL112789 0.83 TSHR (0.63) TSHRCETPSRCPDPK1MTOR
SCHEMBL206610 0.83 TSHR (0.76) TSHRCETPSRCPDPK1MTOR
SCHEMBL10931929 0.83 TSHR (0.63) TSHRCETPSRCPDPK1MTOR
SCHEMBL51316 0.83 TSHR (1.00) TSHRCETPSRCPDPK1MTOR
SCHEMBL27908642 0.83 TSHR (1.00) TSHRCETPSRCPDPK1MTOR
SCHEMBL4219700 0.81 TSHR (0.96) TSHRCETPSRCPDPK1MTOR
SCHEMBL9446520 0.81 TSHR (0.96) TSHRCETPSRCPDPK1MTOR
Hydrochloric Acid SCHEMBL10722992 0.81 TSHR (0.96) TSHRCETPSRCPDPK1MTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230313074-A1 WASHING AND CLEANING AGENTS HAVING IMPROVED ENZYME STABILITY HENKEL AG & CO. KGAA (DE) 2023-10-05 US claimed
EP-4200309-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES ATEA Pharmaceuticals, Inc. (US) 2023-06-28 EP claimed
CN-115884977-A Stereoselective preparation of selected purine phosphoramidates 阿堤亚制药公司 2023-03-31 CN claimed
WO-2022040473-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES Atea Pharmaceuticals, Inc. (US) 2022-02-24 WO claimed
WO-2021013684-A1 DETERGENTS AND CLEANING AGENTS HAVING IMPROVED ENZYME STABILITY HENKEL AG & CO. KGAA (DE) 2021-01-28 WO claimed
CN-106188139-B Tenofovir monobenzyl phosphoric acid amide prodrug, preparation method and application thereof 江苏天士力帝益药业有限公司 2020-02-18 CN claimed
EP-0929636-B1 LIQUID DETERGENTS CONTAINING PROTEOLYTIC ENZYME, PEPTIDE ALDEHYDE AND A SOURCE OF BORIC ACID PROCTER & GAMBLE (US) 2002-12-04 EP claimed
EP-0929639-B1 LIQUID DETERGENTS CONTAINING PROTEOLYTIC ENZYME, PEPTIDE ALDEHYDE AND CALCIUM IONS PROCTER & GAMBLE (US) 2002-11-13 EP claimed
EP-0929636-A1 LIQUID DETERGENTS CONTAINING PROTEOLYTIC ENZYME, PEPTIDE ALDEHYDE AND A SOURCE OF BORIC ACID THE PROCTER & GAMBLE COMPANY (US) 1999-07-21 EP claimed
EP-0929639-A1 LIQUID DETERGENTS CONTAINING PROTEOLYTIC ENZYME, PEPTIDE ALDEHYDE AND CALCIUM IONS THE PROCTER & GAMBLE COMPANY (US) 1999-07-21 EP claimed
WO-1998013459-A1 LIQUID DETERGENTS CONTAINING PROTEOLYTIC ENZYME, PEPTIDE ALDEHYDE AND CALCIUM IONS THE PROCTER & GAMBLE COMPANY (US) 1998-04-02 WO claimed
WO-1998013462-A1 LIQUID DETERGENTS CONTAINING PROTEOLYTIC ENZYME, PEPTIDE ALDEHYDE AND A SOURCE OF BORIC ACID THE PROCTER & GAMBLE COMPANY (US) 1998-04-02 WO claimed
US-20230331751-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES Atea Pharmaceuticals, Inc. (US) 2023-10-19 US disclosed
US-20230313074-A1 WASHING AND CLEANING AGENTS HAVING IMPROVED ENZYME STABILITY HENKEL AG & CO. KGAA (DE) 2023-10-05 US disclosed
WO-2022178428-A9 TARGETED BIFUNCTIONAL DEGRADERS AND METHODS USING SAME YALE UNIVERSITY (US) 2023-08-17 WO disclosed
EP-4200309-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES ATEA Pharmaceuticals, Inc. (US) 2023-06-28 EP disclosed
WO-1998013460-A1 LIQUID DETERGENTS CONTAINING PROTEOLYTIC ENZYME AND PROTEASE INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 1998-04-02 WO disclosed
WO-1998013461-A1 LIQUID LAUNDRY DETERGENT COMPOSITIONS CONTAINING PROTEOLYTIC ENZYME AND PROTEASE INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 1998-04-02 WO disclosed
WO-1998013462-A1 LIQUID DETERGENTS CONTAINING PROTEOLYTIC ENZYME, PEPTIDE ALDEHYDE AND A SOURCE OF BORIC ACID THE PROCTER & GAMBLE COMPANY (US) 1998-04-02 WO disclosed
WO-1998013458-A1 LIQUID DETERGENTS CONTAINING PROTEOLYTIC ENZYME AND PROTEASE INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 1998-04-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331751-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES NUDT1, PNP, ATIC TSHR 3475/4885CETP 4214/4885SRC 3618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.