Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 8/20 | 0.67 |
| ▸ | BCL6 | P41182 | 12/20 | 0.59 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.54 |
| ▸ | JAK1 | P23458 | 1/20 | 0.53 |
| ▸ | JAK3 | P52333 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11937325 | 0.87 | SYK (0.62) | SYKBCL6NCOR2JAK1JAK3 | |
| SCHEMBL1384407 | 0.85 | SYK (0.68) | SYKJAK1JAK3 | |
| SCHEMBL2102264 | 0.84 | SYK (0.62) | SYKBCL6NCOR2JAK1JAK3 | |
| SCHEMBL2102713 | 0.84 | SYK (0.66) | SYKBCL6NCOR2JAK1JAK3 | |
| SCHEMBL2102187 | 0.84 | BCL6 (0.57) | SYKBCL6NCOR2 | |
| SCHEMBL2100735 | 0.84 | BCL6 (0.56) | SYKBCL6NCOR2 | |
| SCHEMBL2103320 | 0.84 | BCL6 (0.56) | SYKBCL6NCOR2 | |
| SCHEMBL19297754 | 0.83 | BCL6 (0.58) | SYKBCL6NCOR2 | |
| SCHEMBL19297723 | 0.82 | BCL6 (0.59) | SYKBCL6NCOR2 | |
| SCHEMBL655635 | 0.82 | BCL6 (0.80) | SYKBCL6NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027238-A2 | JAK KINASE INHIBITORS AND THEIR USES | RIGEL PHARMACEUTICALS, INC. (US) | 2007-03-08 | — | — | WO | disclosed |