Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 12/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.55 |
| ▸ | SYK | P43405 | 4/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | STK17B | O94768 | 1/20 | 0.47 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19297718 | 0.92 | SYK (0.48) | BCL6SYKEGFRPTK2 | |
| SCHEMBL19297725 | 0.90 | SYK (0.56) | BCL6SYKEGFRSTK17BSTK17A | |
| SCHEMBL19297722 | 0.88 | SYK (0.57) | SYKEGFR | |
| SCHEMBL19297748 | 0.86 | BCL6 (0.58) | BCL6NCOR2SYKEGFRSTK17B | |
| SCHEMBL1382932 | 0.86 | SYK (0.53) | SYKEGFRSTK17BSTK17APTK2 | |
| SCHEMBL19297749 | 0.85 | AURKA (0.52) | SYKEGFR | |
| SCHEMBL14607335 | 0.83 | SYK (0.67) | BCL6NCOR2SYK | |
| SCHEMBL19297723 | 0.83 | BCL6 (0.59) | BCL6NCOR2SYKEGFRSTK17B | |
| SCHEMBL655635 | 0.83 | BCL6 (0.80) | BCL6NCOR2SYKEGFRSTK17B | |
| SCHEMBL3183762 | 0.82 | KIF11 (0.45) | BCL6NCOR2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751893-B2 | Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS, INC. (US) | 2017-09-05 | — | — | US | claimed |