Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27700119 | 0.90 | TSHR (0.64) | ALDH1A1LMNATSHRKDM4EUSP2 | |
| Improsulfan SCHEMBL27654142 | 0.88 | TSHR (0.61) | ALDH1A1LMNATSHRKDM4EUSP2 | |
| Improsulfan SCHEMBL8954 | 0.88 | USP2 (0.67) | ALDH1A1LMNATSHRKDM4EUSP2 | |
| Improsulfan SCHEMBL10628525 | 0.86 | USP2 (0.64) | ALDH1A1LMNATSHRKDM4EUSP2 | |
| Improsulfan SCHEMBL5886799 | 0.86 | TSHR (0.71) | ALDH1A1LMNATSHRKDM4EUSP2 | |
| Improsulfan SCHEMBL844581 | 0.86 | USP2 (0.64) | ALDH1A1LMNATSHRKDM4EUSP2 | |
| SCHEMBL31599480 | 0.83 | TSHR (0.75) | ALDH1A1LMNATSHRKDM4EUSP2 | |
| SCHEMBL14608856 | 0.81 | TSHR (0.71) | ALDH1A1LMNATSHRKDM4EUSP2 | |
| SCHEMBL21616872 | 0.81 | TSHR (0.71) | ALDH1A1LMNATSHRKDM4EUSP2 | |
| SCHEMBL223147 | 0.81 | USP2 (0.70) | ALDH1A1LMNATSHRKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1754712-A2 | Transcobalamin binding conjugates useful for treating abnormal cellular proliferation | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2007-02-21 | — | — | EP | disclosed |