Improsulfan

Improsulfan

SCHEMBL8954

CS(=O)(=O)OCCCNCCCOS(C)(=O)=O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.67
TSHR P16473 2/20 0.67
KDM4E B2RXH2 1/20 0.67
ALDH1A1 P00352 1/20 0.67
LMNA P02545 1/20 0.67
MMP9 P14780 1/20 0.67
ALOX15 P16050 1/20 0.67
CA1 P00915 16/20 0.35
CA2 P00918 16/20 0.35
CA9 Q16790 14/20 0.35
SAT1 P21673 1/20 0.34
CA12 O43570 5/20 0.33
CA7 P43166 5/20 0.33
CA14 Q9ULX7 5/20 0.33
CA3 P07451 4/20 0.33
CA4 P22748 4/20 0.33
CA6 P23280 4/20 0.33
CA5A P35218 4/20 0.33
CA5B Q9Y2D0 4/20 0.33
DRD2 P14416 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Improsulfan SCHEMBL10628525 0.98 USP2 (0.64) USP2TSHRKDM4EALDH1A1LMNA
Improsulfan SCHEMBL5886799 0.98 TSHR (0.71) USP2TSHRKDM4EALDH1A1LMNA
Improsulfan SCHEMBL844581 0.98 USP2 (0.64) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL27700119 0.98 TSHR (0.64) USP2TSHRKDM4EALDH1A1LMNA
Improsulfan SCHEMBL27654142 0.95 TSHR (0.61) USP2TSHRKDM4EALDH1A1LMNA
Improsulfan SCHEMBL6228502 0.91 KDM4E (0.56) USP2TSHRKDM4EALDH1A1LMNA
Improsulfan SCHEMBL28223296 0.89 KDM4E (0.54) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL14608855 0.88 ALDH1A1 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL5551062 0.88 ALOX15 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL2640956 0.83 USP2 (0.64) USP2TSHRKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 27864 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748859-A2 CHEMICALLY AND PHOTOCHEMICALLY INITIATED CELL MEMBRANE BLEBBING TO INDUCE CELL VESICLE PRODUCTION, MODIFICATIONS THEREOF, AND USES THEREOF The Regents of the University of California (US) 2026-05-27 EP claimed
EP-4743490-A1 HUMANIZED ANTI-CD7 ANTIBODY Christian-Albrechts-Universität zu Kiel (DE) 2026-05-20 EP claimed
WO-2026099502-A1 NOVEL DRUG CONJUGATES FOR TESTING CELLULAR DRUG UPTAKE Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2026-05-15 WO claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
EP-3515892-B1 COMPOUNDS AND METHODS FOR IDO AND TDO MODULATION, AND INDICATIONS THEREFOR PLEXXIKON INC (US) 2026-04-15 EP claimed
US-20260085100-A1 METHODS OF ANTIGEN PRODUCTION THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) 2026-03-26 US claimed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 US claimed
EP-4698185-A1 METHODS AND SYSTEMS FOR IMPROVING ANTI-CANCER THERAPIES Osasuna Therapeutics SA (CH) 2026-02-25 EP claimed
EP-4694909-A1 METHODS OF MODULATING THE EPITHELIAL-MESENCHYMAL TRANSITION RS Oncology, LLC (US) 2026-02-18 EP claimed
EP-4676544-A1 ANTIBODY-DRUG CONJUGATE COMPRISING ANTIBODIES AGAINST HUMAN L1CAM AND USES THEREOF LigaChem Biosciences Inc. (KR) 2026-01-14 EP claimed
WO-1999058126-A1 USE OF NEOMYCIN FOR TREATING ANGIOGENESIS-RELATED DISEASES THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) 1999-11-18 WO claimed
WO-1999042578-A2 MODULATION OF CELL PROLIFERATION, METHODS AND REAGENTS COLD SPRING HARBOR LABORATORY (US) 1999-08-26 WO claimed
EP-0875246-A1 Pharmaceutical preparation of ascorbic acid derivatives for medical treatment of cancer SHOWA DENKO KABUSHIKI KAISHA (JP) 1998-11-04 EP claimed
EP-0319781-B1 Portable transmitter for the electromagnetic transmission of coded pulses, and tuned receiver therefor GIMBEL KARL HEINZ DIPL ING (DE) 1996-06-19 EP claimed
EP-0174014-B1 OPTICAL STAR COUPLER AND METHOD FOR MANUFACTURING THE SAME HITACHI, LTD. (JP) 1992-03-18 EP claimed
US-4837760-A Communications system with protection switching using individual selectors NORTHERN TELECOM LIMITED (CA) 1989-06-06 US claimed
EP-0203893-B1 MODULAR WORKPIECE-FEED MECHANISM FOR USE WITH WOODWORKING MACHINERY SAMCO INDUSTRIA S.p.A. (IT) 1989-01-25 EP claimed
US-4628479-A Terminal with memory write protection ZENITH ELECTRONICS CORPORATION (US) 1986-12-09 US claimed
EP-0089533-B1 STACK OF ANGLE-FORMED CORNER PROTECTORS Fr. Sander GmbH & Co. (DE) 1986-10-15 EP claimed
US-4379493-A Method and apparatus for preventing wireline kinking in a directional drilling system THIBODEAUX GENE 1983-04-12 US claimed