Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3763147 | 0.88 | PKM (0.65) | PKMNPSR1LMNAGAAALDH1A1 | |
| SCHEMBL3772228 | 0.85 | KMT2A (0.63) | PKMNPSR1LMNAGAAALDH1A1 | |
| SCHEMBL3762814 | 0.81 | MAPT (0.78) | PKMNPSR1LMNAGAAALDH1A1 | |
| SCHEMBL26171578 | 0.79 | PKM (0.60) | PKMNPSR1LMNAGAAALDH1A1 | |
| SCHEMBL25122016 | 0.79 | PKM (0.60) | PKMNPSR1LMNAGAAALDH1A1 | |
| SCHEMBL8230438 | 0.78 | MAPT (0.73) | PKMNPSR1LMNAGAAALDH1A1 | |
| SCHEMBL3440160 | 0.78 | GFER (0.74) | PKMNPSR1GAAALDH1A1MAPT | |
| SCHEMBL3768253 | 0.78 | MAPT (0.72) | PKMNPSR1LMNAGAAALDH1A1 | |
| SCHEMBL10725624 | 0.78 | CHRM2 (0.65) | LMNAGAAALDH1A1MAPTKDM4E | |
| SCHEMBL20354370 | 0.77 | GFER (0.72) | PKMNPSR1LMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007016496-A2 | DIPIPERAZINYL KETONES AND RELATED ANALOGUES | NEUROGEN CORPORATION (US) | 2007-02-08 | — | — | WO | disclosed |