Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222920 | 0.83 | PREP (0.53) | PREPUSP2SMN1; SMN2ESR2NR1H2 | |
| SCHEMBL173435 | 0.71 | USP2 (0.49) | PREPUSP2SMN1; SMN2ESR2HPGD | |
| SCHEMBL5548370 | 0.70 | — | — | |
| SCHEMBL14609267 | 0.70 | — | — | |
| SCHEMBL6348608 | 0.70 | PREP (0.46) | PREPUSP2SMN1; SMN2NR1H2MAPT | |
| SCHEMBL2496477 | 0.70 | USP2 (0.52) | PREPUSP2SMN1; SMN2ESR2NR1H2 | |
| SCHEMBL1242684 | 0.70 | USP2 (0.52) | PREPUSP2SMN1; SMN2ESR2NR1H2 | |
| SCHEMBL4693378 | 0.68 | HPGD (0.46) | PREPUSP2SMN1; SMN2ESR2ALDH1A1 | |
| SCHEMBL15624147 | 0.67 | HPGD (0.49) | PREPUSP2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL15624132 | 0.67 | HPGD (0.49) | PREPUSP2SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276491-B9 | TAMANDARIN AND DIDEMNIN ANALOGS AND METHODS OF MAKING AND USING THEM | UNIV PENNSYLVANIA (US) | 2007-02-28 | — | — | EP | disclosed |