SCHEMBL173435

SCHEMBL173435

CC(C)(C)OC(=O)N1CC=CCC1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
PREP P48147 1/20 0.47
HPGD P15428 1/20 0.41
DPP4 P27487 2/20 0.41
DPP7 Q9UHL4 2/20 0.41
DPP8 Q6V1X1 1/20 0.41
GPR119 Q8TDV5 1/20 0.40
CTSK P43235 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ESR2 Q92731 1/20 0.40
RECQL P46063 1/20 0.40
EPHX1 P07099 1/20 0.40
PDK4 Q16654 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27630753 0.95 USP2 (0.45) USP2SMN1; SMN2PREPHPGDDPP4
SCHEMBL4773530 0.90 USP2 (0.58) USP2SMN1; SMN2HPGDGPR119MEN1
SCHEMBL4693378 0.89 HPGD (0.46) USP2SMN1; SMN2PREPHPGDGPR119
SCHEMBL2596349 0.89 PTPN2 (0.48) USP2SMN1; SMN2PREPGPR119MEN1
SCHEMBL15624132 0.88 HPGD (0.49) USP2SMN1; SMN2PREPHPGDCTSK
SCHEMBL15624147 0.88 HPGD (0.49) USP2SMN1; SMN2PREPHPGDCTSK
SCHEMBL17248133 0.86 HPGD (0.51) USP2SMN1; SMN2PREPHPGDCTSK
SCHEMBL222920 0.86 PREP (0.53) USP2SMN1; SMN2PREPHPGDGPR119
SCHEMBL29877008 0.84 USP2 (0.45) USP2SMN1; SMN2PREPHPGDGPR119
SCHEMBL11913651 0.84 USP2 (0.51) USP2SMN1; SMN2HPGDGPR119MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 821 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118541362-A Pyridazinylamino derivatives as ALK5 inhibitors 奇斯药制品公司 2024-08-23 CN claimed
CN-114829344-B Pyrimidine derivatives and pharmaceutical compositions containing the same 韩国化学研究院 2024-08-13 CN claimed
CN-114746411-B Substituted tricyclic compounds 印度鲁宾有限公司 2024-06-25 CN claimed
CN-114085219-B Synthesis of (1S, 6R) -8-benzyl-7, 9-dioxo-2, 8-diazabicyclo [4.3.0] nonane 武汉理工大学 2023-08-01 CN claimed
EP-3741757-B1 DIHYDROINDOLIZINONE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2023-07-26 EP claimed
CN-114829344-A Novel pyrimidine derivative and use thereof 韩国化学研究院 2022-07-29 CN claimed
CN-114746411-A Substituted tricyclic compounds 印度鲁宾有限公司 2022-07-12 CN claimed
CN-114085219-A Synthesis of (1S,6R) -8-benzyl-7, 9-dioxo-2, 8-diazabicyclo [4.3.0] nonane 武汉理工大学 2022-02-25 CN claimed
CN-119528901-B Thiazole compound, dessumo and/or deubiquitinase inhibitor, and preparation methods and applications thereof Shanghai tongji hospital (CN) 2026-05-26 CN disclosed
US-12378232-B2 Cyclin dependent kinase inhibitors PFIZER INC. (US) 2025-08-05 US disclosed
EP-4587435-A1 MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS Cullgen (Shanghai), Inc. (CN) 2025-07-23 EP disclosed
CN-120152967-A Bifunctional compounds containing 2, 5-substituted pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway 霖康疗法公司 2025-06-13 CN disclosed
US-20250171462-A1 COMPOUNDS, COMPOSITIONS, AND METHODS TENVIE THERAPEUTICS, INC. 2025-05-29 US disclosed
CN-115335373-B Compounds and uses thereof 福宏治疗公司 2025-05-20 CN disclosed
CN-1139928-A Novel compounds FUJISAWA PHARMACEUTICAL CO (JP) 1997-01-08 CN disclosed
EP-0737193-A1 PYRAZOLOPYRIDINE ADENOSINE ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-10-16 EP disclosed
US-5554752-A SPIRO FUSED PIPERIDINES CAPABLE OF BINDING TO A VESAMICOL RECEPTOR AND HAVING ANTICHOLINERGIC PROPERTIES REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1996-09-10 US disclosed
US-5457207-A Anticholinergic agents REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1995-10-10 US disclosed
WO-1995018128-A1 PYRAZOLOPYRIDINE ADENOSINE ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-07-06 WO disclosed
WO-1995009631-A1 SPIROVESAMICOLS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1995-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171462-A1 COMPOUNDS, COMPOSITIONS, AND METHODS SARM1, SARS1, TIAM1 USP2 2412/4885SMN1; SMN2 774/4885PREP 2455/4885
US-12378232-B2 Cyclin dependent kinase inhibitors CCNY, CCNI, CCNK USP2 2158/4885SMN1; SMN2 4086/4885PREP 3006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.