Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1242684 | 0.86 | USP2 (0.52) | PREPUSP2SMN1; SMN2NR1H2HPGD | |
| SCHEMBL2496477 | 0.86 | USP2 (0.52) | PREPUSP2SMN1; SMN2NR1H2HPGD | |
| SCHEMBL173435 | 0.86 | USP2 (0.49) | PREPUSP2SMN1; SMN2HPGDCTSK | |
| SCHEMBL6348608 | 0.84 | PREP (0.46) | PREPUSP2SMN1; SMN2NR1H2HPGD | |
| SCHEMBL4693378 | 0.83 | HPGD (0.46) | PREPUSP2SMN1; SMN2HPGDCTSK | |
| SCHEMBL14609367 | 0.83 | PREP (0.40) | PREPUSP2SMN1; SMN2NR1H2HPGD | |
| SCHEMBL6203338 | 0.82 | CTSK (0.50) | PREPUSP2SMN1; SMN2NR1H2HPGD | |
| SCHEMBL15624132 | 0.82 | HPGD (0.49) | PREPUSP2SMN1; SMN2HPGDCTSK | |
| SCHEMBL15624147 | 0.82 | HPGD (0.49) | PREPUSP2SMN1; SMN2HPGDCTSK | |
| Acetic Acid SCHEMBL27630753 | 0.82 | USP2 (0.45) | PREPUSP2SMN1; SMN2HPGDCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1094 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930872-A | Catalyst system, prepolymerized catalyst composition and olefin polymerization process | 中国石油化工股份有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119930869-A | Auxiliary agent for olefin polymerization, olefin catalyst system, prepolymerized catalyst composition and olefin polymerization method | 中国石油化工股份有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119930866-A | Catalyst component containing pyrroline compound, preparation method thereof, olefin polymerization catalyst, olefin polymerization method and olefin polymer | 中国石油化工股份有限公司 | 2025-05-06 | — | — | CN | claimed |
| US-20250051272-A1 | METHOD FOR CONTINUOUSLY SYNTHESIZING N-BOC-2,5-DIHYDROPYRROLE | ASYMCHEM LIFE SCIENCE (TIANJIN) CO., LTD. (CN) | 2025-02-13 | — | — | US | claimed |
| EP-4434965-A1 | METHOD FOR CONTINUOUSLY SYNTHESIZING N-BOC-2,5-DIHYDROPYRROLE | Asymchem Life Science (Tianjin) Co., Ltd (CN) | 2024-09-25 | — | — | EP | claimed |
| WO-2023178754-A1 | METHOD FOR CONTINUOUSLY SYNTHESIZING N-BOC-2,5-DIHYDROPYRROLE | 凯莱英生命科学技术(天津)有限公司 | 2023-09-28 | — | — | WO | claimed |
| CN-114394927-B | Process for the preparation of 6, 6-dimethyl-3-azabicyclo [3.1.0] hexane-2-carboxylic acid | 汉瑞药业(荆门)有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-114349676-B | Method for continuously synthesizing N-Boc-2, 5-pyrroline | 凯莱英生命科学技术(天津)有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-113185440-B | Preparation method of medical intermediate N-BOC-3-pyrroline | 南京德克瑞医药化工有限公司 | 2022-04-29 | — | — | CN | claimed |
| CN-114394927-A | Process for preparing 6, 6-dimethyl-3-azabicyclo [3.1.0] hexane-2-carboxylic acid | 汉瑞药业(荆门)有限公司 | 2022-04-26 | — | — | CN | claimed |
| CN-105732458-B | Pyrrole amides class compound and preparation method thereof and purposes | 成都先导药物开发有限公司 | 2019-06-07 | — | — | CN | claimed |
| CN-105732459-B | Pyrrole amides class compound and preparation method thereof and purposes | 成都先导药物开发有限公司 | 2019-05-31 | — | — | CN | claimed |
| CN-105801464-B | Pyrrole amides class compound and preparation method thereof and purposes | 成都先导药物开发有限公司 | 2019-05-28 | — | — | CN | claimed |
| CN-105732597-B | A kind of midbody compound and the preparation method and application thereof preparing pyrrole amides class compound | 成都先导药物开发有限公司 | 2019-01-01 | — | — | CN | claimed |
| EP-2382214-B1 | METHOD OF PREPARING (+)-1,4-DIHYDRO-7-[(3S,4S)-3-METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OXO-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID | SUNESIS PHARMACEUTICALS INC (US) | 2017-07-19 | — | — | EP | claimed |
| US-8497282-B2 | Method of preparing (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid | SUNESIS PHARMACEUTICALS, INC. (US) | 2013-07-30 | — | — | US | claimed |
| CN-103130706-A | Preparing method of 6-oxo-3-aza-bicyclo[3,2,0]heptane-3-carboxylic acid tert-butyl ester | WUXI APPTEC CO LTD | 2013-06-05 | — | — | CN | claimed |
| EP-2382214-A1 | METHOD OF PREPARING (+)-1,4-DIHYDRO-7-Ý(3S,4S)-3METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL¨-4-OXO-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID | Sunesis Pharmaceuticals, Inc. (US) | 2011-11-02 | — | — | EP | claimed |
| US-20100203162-A1 | Method of preparing (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid | SUNESIS PHARMACEUTICALS, INC. | 2010-08-12 | — | — | US | claimed |
| WO-2010078294-A1 | METHOD OF PREPARING (+)-1,4-DIHYDRO-7-[(3S,4S)-3METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OXO-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID | SUNESIS PHARMACEUTICAL, INC. (US) | 2010-07-08 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100203162-A1 | Method of preparing (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid | CYP7A1, MT-ND1, DNM1 | PREP 1516/4885USP2 4595/4885SMN1; SMN2 399/4885 |
| US-20250051272-A1 | METHOD FOR CONTINUOUSLY SYNTHESIZING N-BOC-2,5-DIHYDROPYRROLE | UROD, PKD2, PKD1 | PREP 742/4885USP2 958/4885SMN1; SMN2 738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.