Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.60 |
| ▸ | ITGAV | P06756 | 2/20 | 0.60 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.60 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.60 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14609323 | 0.91 | ITGB3 (0.58) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL14609159 | 0.89 | ITGB3 (0.73) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL14609586 | 0.89 | ITGB3 (0.64) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL14609135 | 0.84 | ITGB3 (0.68) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL14609161 | 0.83 | PTPN1 (0.59) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL14609347 | 0.80 | ITGB3 (0.78) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL14609237 | 0.80 | ITGB3 (0.73) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL14609157 | 0.80 | ITGB3 (0.72) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL14609334 | 0.79 | ITGB3 (0.71) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL14609131 | 0.78 | ITGB3 (0.77) | ITGB3ITGAVITGB1ITGA5ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135374-B9 | BENZIMIDAZOLE COMPOUNDS THAT ARE VITRONECTIN RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2007-02-21 | — | — | EP | disclosed |