Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.51 |
| ▸ | ITGAV | P06756 | 2/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.51 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.51 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14609323 | 0.83 | ITGB3 (0.58) | PTPN1ITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL14609587 | 0.83 | ITGB3 (0.60) | PTPN1ITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL14609230 | 0.80 | ITGB3 (0.62) | PTPN1ITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL14609586 | 0.80 | ITGB3 (0.64) | PTPN1ITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL19378078 | 0.79 | PTPN1 (0.75) | PTPN1PPARAPPARGALDH1A1PIN1 | |
| SCHEMBL11096309 | 0.79 | PTPN1 (0.75) | PTPN1PPARAPPARGALDH1A1PIN1 | |
| SCHEMBL14025800 | 0.77 | MAPT (0.66) | ITGB3ITGAVTSHRMAPK10KMT2A | |
| SCHEMBL6382995 | 0.77 | PPARA (0.57) | ITGAVPPARAPPARGPPARD | |
| SCHEMBL5207117 | 0.77 | PTPN1 (0.47) | PTPN1ITGB3ITGAVTSHRMAPK10 | |
| SCHEMBL3507845 | 0.74 | PTPN1 (0.56) | PTPN1BCHEATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135374-B9 | BENZIMIDAZOLE COMPOUNDS THAT ARE VITRONECTIN RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2007-02-21 | — | — | EP | disclosed |