Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.57 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.52 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14610001 | 0.89 | TRPM8 (0.65) | TRPM8SGMS2LPAR1 | |
| SCHEMBL14610257 | 0.86 | TRPM8 (0.64) | TRPM8SGMS2LPAR1 | |
| SCHEMBL14610217 | 0.84 | TRPM8 (0.60) | TRPM8SLC1A5MAPTLPAR1 | |
| SCHEMBL14610621 | 0.84 | TRPM8 (0.62) | TRPM8SGMS2SLC1A5 | |
| SCHEMBL14610589 | 0.83 | TRPM8 (0.59) | TRPM8SLC1A5ALDH1A1RAF1MAP2K1 | |
| SCHEMBL14610018 | 0.83 | TRPM8 (0.59) | TRPM8SGMS2LPAR1 | |
| SCHEMBL14610010 | 0.82 | TRPM8 (0.58) | TRPM8SGMS2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5372786 | 0.82 | TRPM8 (0.58) | TRPM8SLC1A5ALDH1A1RAF1MAP2K1 | |
| SCHEMBL14609962 | 0.82 | TRPM8 (0.75) | TRPM8SGMS2LPAR1 | |
| SCHEMBL14610072 | 0.81 | TRPM8 (0.56) | TRPM8SLC1A5ALDH1A1MAPTLPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017093-A1 | SUBSTITUTED 2-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |