Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.50 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14610209 | 0.94 | TRPM8 (0.55) | TRPM8LPAR1PTGER1PTGER4PTGER3 | |
| SCHEMBL14610005 | 0.91 | TRPM8 (0.47) | TRPM8SLC1A5CARM1PRMT1KDM4E | |
| SCHEMBL14610617 | 0.89 | TRPM8 (0.50) | TRPM8SLC1A5CARM1PRMT1KDM4E | |
| SCHEMBL14610589 | 0.87 | TRPM8 (0.59) | TRPM8SLC1A5CARM1PRMT1KDM4E | |
| Hydrochloric Acid SCHEMBL5372786 | 0.86 | TRPM8 (0.58) | TRPM8SLC1A5CARM1PRMT1KDM4E | |
| SCHEMBL14610215 | 0.84 | TRPM8 (0.52) | TRPM8SLC1A5CARM1PRMT1KDM4E | |
| SCHEMBL14610625 | 0.84 | TRPM8 (0.58) | TRPM8SLC1A5CARM1PRMT1KDM4E | |
| SCHEMBL14610621 | 0.84 | TRPM8 (0.62) | TRPM8SLC1A5CARM1PRMT1PTGER1 | |
| SCHEMBL14610622 | 0.83 | TRPM8 (0.52) | TRPM8 | |
| SCHEMBL14609974 | 0.81 | TRPM8 (0.53) | TRPM8SLC1A5CARM1PRMT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017093-A1 | SUBSTITUTED 2-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |