Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14610589 | 0.87 | TRPM8 (0.59) | TRPM8LPAR1KDM4ESLC1A5CARM1 | |
| Hydrochloric Acid SCHEMBL5372786 | 0.86 | TRPM8 (0.58) | TRPM8LPAR1KDM4ESLC1A5CARM1 | |
| SCHEMBL14610621 | 0.86 | TRPM8 (0.62) | TRPM8SLC1A5CARM1PRMT1PTGER1 | |
| SCHEMBL14610208 | 0.84 | TRPM8 (0.50) | TRPM8LPAR1KDM4ESLC1A5CARM1 | |
| SCHEMBL14610617 | 0.84 | TRPM8 (0.50) | TRPM8KDM4ESLC1A5CARM1PRMT1 | |
| SCHEMBL14610625 | 0.84 | TRPM8 (0.58) | TRPM8LPAR1KDM4ESLC1A5CARM1 | |
| SCHEMBL14609974 | 0.84 | TRPM8 (0.53) | TRPM8KDM4ESLC1A5CARM1PRMT1 | |
| SCHEMBL14610001 | 0.82 | TRPM8 (0.65) | TRPM8LPAR1KDM4EHTT | |
| SCHEMBL14610010 | 0.82 | TRPM8 (0.58) | TRPM8PTGER1HTTPTGER4PTGER3 | |
| SCHEMBL14610011 | 0.82 | TRPM8 (0.58) | TRPM8LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017093-A1 | SUBSTITUTED 2-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |