Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13871657 | 0.89 | ALDH1A1 (0.34) | ALDH1A1KDM4EHPGDATMHSD17B10 | |
| SCHEMBL4105346 | 0.79 | KMT2A (0.34) | ALDH1A1HPGDHSD17B10KMT2ACASP3 | |
| SCHEMBL14610314 | 0.71 | KMT2A (0.33) | ALDH1A1HPGDHSD17B10KMT2ACASP3 | |
| SCHEMBL13871658 | 0.69 | FLT3 (0.32) | KMT2ACASP3SENP8SENP7SENP6 | |
| SCHEMBL22607895 | 0.68 | USP2 (0.47) | ALDH1A1KDM4EHPGDATMHSD17B10 | |
| SCHEMBL31322733 | 0.67 | HPGD (0.50) | ALDH1A1KDM4EHPGDATMHSD17B10 | |
| SCHEMBL1529648 | 0.66 | USP2 (0.51) | ALDH1A1KDM4EHPGDATMHSD17B10 | |
| SCHEMBL22607873 | 0.66 | USP2 (0.47) | ALDH1A1KDM4EHPGDATMHSD17B10 | |
| SCHEMBL4688336 | 0.65 | PTGER3 (0.49) | — | |
| SCHEMBL4991114 | 0.65 | PTGER3 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007014454-A1 | EP4 RECEPTOR AGONIST, COMPOSITIONS AND METHODS THEREOF | MERCK FROSST CANADA LTD. (CA) | 2007-02-08 | — | — | WO | disclosed |