Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4105346 | 0.92 | KMT2A (0.34) | KMT2AMAPK1CASP3SENP8SENP7 | |
| SCHEMBL13871659 | 0.92 | KMT2A (0.34) | KMT2AMAPK1CASP3SENP8SENP7 | |
| SCHEMBL13871658 | 0.89 | FLT3 (0.32) | KMT2AMAPK1CASP3SENP8SENP7 | |
| SCHEMBL13871657 | 0.81 | ALDH1A1 (0.34) | KMT2AMAPK1CASP3SENP8SENP7 | |
| SCHEMBL4114149 | 0.76 | PTGER4 (0.38) | — | |
| SCHEMBL4106475 | 0.72 | PTGER4 (0.34) | — | |
| SCHEMBL14610312 | 0.71 | ALDH1A1 (0.36) | KMT2ACASP3SENP8SENP7SENP6 | |
| SCHEMBL4116123 | 0.70 | PTGER4 (0.41) | — | |
| SCHEMBL4112956 | 0.69 | PTGER4 (0.46) | — | |
| SCHEMBL4105625 | 0.68 | PTGER4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007014454-A1 | EP4 RECEPTOR AGONIST, COMPOSITIONS AND METHODS THEREOF | MERCK FROSST CANADA LTD. (CA) | 2007-02-08 | — | — | WO | disclosed |