Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 20/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14610868 | 0.75 | NR1H3 (0.40) | CYP19A1 | |
| SCHEMBL14610148 | 0.74 | NR1H3 (0.39) | CYP19A1 | |
| SCHEMBL12704706 | 0.71 | PTPN1 (0.59) | — | |
| SCHEMBL14610161 | 0.70 | NR1H3 (0.38) | — | |
| SCHEMBL12704637 | 0.69 | SOD1 (0.47) | — | |
| SCHEMBL14610500 | 0.67 | NR1H3 (0.38) | — | |
| SCHEMBL10224357 | 0.67 | NR1H3 (0.38) | CYP19A1 | |
| SCHEMBL18688311 | 0.63 | CYP19A1 (0.35) | CYP19A1 | |
| SCHEMBL12522461 | 0.62 | PTPN1 (0.34) | — | |
| SCHEMBL17299251 | 0.61 | ESR1 (0.40) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007015757-A2 | INTERLEUKIN-1 AND TUMOR NECROSIS FACTOR-A MODULATORS; SYNTHESES OF SUCH MODULATORS AND METHODS OF USING SUCH MODULATORS | NEREUS PHARMACEUTICALS, INC. (US) | 2007-02-08 | — | — | WO | disclosed |