Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | RAF1 | P04049 | 2/20 | 0.58 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.58 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5305560 | 0.94 | MRGPRX4 (0.61) | TRPM8NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14078347 | 0.91 | TRPM8 (0.69) | TRPM8NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14610697 | 0.91 | RAF1 (0.61) | TRPM8NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14078352 | 0.89 | TRPM8 (0.64) | TRPM8NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14610662 | 0.88 | LPAR1 (0.54) | TRPM8NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14610918 | 0.88 | TRPM8 (0.68) | TRPM8NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14610712 | 0.88 | NPC1 (0.61) | NPC1RAB9AHPGDSMN1; SMN2RAF1 | |
| Hydrochloric Acid SCHEMBL5114925 | 0.88 | TRPM8 (0.62) | TRPM8NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14610939 | 0.87 | TRPM8 (0.52) | TRPM8NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14610733 | 0.87 | RAF1 (0.58) | TRPM8NPC1RAB9AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017092-A1 | SUBSTITUTED 4-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |